产品索引
        

        
产品数据 
        

          

            

              

                货号
              
              
LPA35924
              

                文献
              
              

                详细请查看官网 
              
            

            

              

                产品名称
              
              
Prostate-Specific Membrane Antigen(PSMA) (ABT-PSMA) mouse Monoclonal Antibody
            
            

              

                中文名称
              
              
Prostate-Specific Membrane gen(PSMA) (ABT-PSMA) 小鼠单克隆抗体
            
            

              
规格
              
100ug
              
适应种属
              
Human
            
            

              

                纯化方法
              
              
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
              

                UniProt ID
              
              

                
              
            
            

              

                浓度
              
              
1mg/ml
              

                宿主
              
              
Mouse/IgG1
            
            

              

                克隆性
              
              
Monoclonal
              

                亚型
              
              
IgG1
            
            

              

                免疫原
              
              
Synthesized peptide derived from human Prostate-Specific Membrane Antigen(PSMA) 
              

                分子量
              
              

            
            

              

                验证应用
              
              
IHC-p,WB
            
            

              

                验证应用
              
              
Liquid
            
            

              

                建议稀释比例
              
              
IHC-p 1:100-500，WB 1:500-2000
              

                存储条件
              
              
-20°C/1 year
            
            

              

                偶联物
              
              
Unconjugated 
              

                储存溶液
              
              
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. 
            
            

              

                运输条件
              
              

                所有可选规格：常温运输或根据产品储存温度要求用蓝冰运输。
              
            
            

              

                注意事项
              
              

                该产品仅供科研使用
              
            
          
        
        

        
背景介绍
        
folate hydrolase 1(FOLH1)       Homo sapiens    This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alter

        
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